Endometriosis and Brain Fog: What the Science Is Finally Saying
For years, people with endometriosis have reported a frustrating and often dismissed symptom: brain fog. That cloudy, hard-to-concentrate, where-did-I-put-my-keys kind of feeling. Now, science is starting to back us up — and it's about time.
A groundbreaking study published in Frontiers in Systems Neuroscience explored how chronic pelvic pain caused by endometriosis may actually affect brain function, especially around memory, attention, and cognitive control.
🧬 What Did the Study Find?
Researchers studied the brain activity of women living with endometriosis and chronic pelvic pain using something called event-related potentials (ERPs) - a way to measure how our brain responds to specific tasks.
They found that two specific ERP components (P3a and P3b), which are closely linked to attention and working memory, were reduced in people with endo. In simpler terms: the brain was having to work harder to stay focused - and it was struggling.
Interestingly, while their brain signals showed strain, the participants didn’t always perform worse on tasks. This suggests that the brain may be compensating in some way, trying to push through despite the pain.
🧠 Why It Matters
This study is a huge validation for anyone who's ever felt like they were "losing it" during a flare-up. It confirms that the pain of endo isn’t just physical - it can affect how we think and feel.
Pain drains cognitive resources. And when you’re battling chronic pain day in and day out, it’s no wonder your brain might start to lag behind. This research shows that brain fog with endo isn't all in your head - it is your head.
🔗 The Research
Study Title: Neuronal Correlates of Cognitive Control Are Altered in Women With Endometriosis and Chronic Pelvic Pain
Journal: Frontiers in Systems Neuroscience
Read the full study here:
👉 Link to full article
💛 Final Thoughts
Whether it's brain fog, fatigue, or chronic pain, endometriosis impacts far more than just reproductive health. If you're struggling to concentrate, forget words mid-sentence, or feel like you're not as sharp as usual - you're not alone, and you're not imagining it.
At UndoEndo, we’re committed to sharing science-backed insights and helping you feel seen, supported, and informed.